Description

5-[[5-(4-Fluoro-2-Hydroxyphenyl)-2-Furanyl]Methylene]-2,4-Thiazolidinedione is a high-purity synthetic organic compound belonging to the thiazolidinedione class, a group of molecules known for their significant biological activity. This compound serves as a critical advanced pharmaceutical intermediate or research-grade reference standard for the development of novel therapeutic agents. It is primarily needed by pharmaceutical R&D laboratories, contract research organizations (CROs), and academic research institutions focused on metabolic and endocrine disorders.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel thiazolidinedione-based drug candidates targeting PPARγ receptors.
• Biochemical Research: Reference standard for in-vitro and in-vivo studies investigating insulin sensitization, glucose metabolism, and adipocyte differentiation.
• Drug Discovery: Core scaffold for medicinal chemistry programs aimed at developing next-generation treatments for Type 2 Diabetes and related metabolic syndromes.
• Analytical Standard: High-purity material for use in HPLC, LC-MS, and NMR as a calibration standard for method development and quality control.
• Academic Research: Used in university laboratories for fundamental research on the structure-activity relationships (SAR) of thiazolidinedione derivatives.

Basic Information

Product Name	5-[[5-(4-Fluoro-2-Hydroxyphenyl)-2-Furanyl]Methylene]-2,4-Thiazolidinedione
CAS No.	900515-16-4
Molecular Formula	C14H8FNO4S
Molecular Weight	305.28 g/mol
Synonyms	5-[(5-(4-Fluoro-2-hydroxyphenyl)furan-2-yl)methylene]thiazolidine-2,4-dione; (5Z)-5-[[5-(4-Fluoro-2-hydroxyphenyl)-2-furanyl]methylene]-2,4-thiazolidinedione; FHPFT; 4-Fluoro-2-hydroxybenzofuranyl thiazolidinedione derivative; TZD Derivative 900515-16-4; PPARγ Ligand Intermediate; 2,4-Thiazolidinedione, 5-[[5-(4-fluoro-2-hydroxyphenyl)-2-furanyl]methylene]-
EINECS	Contact for details

Quality Control

Our 5-[[5-(4-Fluoro-2-Hydroxyphenyl)-2-Furanyl]Methylene]-2,4-Thiazolidinedione is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. A detailed Certificate of Analysis (COA) is provided with each shipment, ensuring traceability and compliance with research and development standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.