Description

(1H-Pyrrolo[2,3-B]Pyridin-5-Ylmethyl)-Carbamic Acid tert-Butyl Ester CAS NO 900514-09-2 is a high-purity, protected amine derivative belonging to the pyrrolopyridine class of heterocyclic compounds. This advanced pharmaceutical intermediate is critical for the synthesis of complex molecules, offering a versatile building block for medicinal chemistry research and development. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and biotechnology industries for creating novel active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the development of kinase inhibitors and other targeted therapeutic agents.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Process Chemistry: Used in the scale-up and optimization of synthetic routes for candidate drugs during preclinical and clinical development phases.
• Bioconjugation: The protected amine functionality allows for selective deprotection and subsequent conjugation to biomolecules or other chemical entities.
• Chemical Biology Probes: Employed in the synthesis of molecular probes for studying biological pathways and target engagement.

Basic Information

Product Name	(1H-Pyrrolo[2,3-B]Pyridin-5-Ylmethyl)-Carbamic Acid tert-Butyl Ester
CAS No.	900514-09-2
Molecular Formula	C13H17N3O2
Molecular Weight	247.29 g/mol
Synonyms	tert-Butyl N-[(1H-pyrrolo[2,3-b]pyridin-5-yl)methyl]carbamate; 5-[[(tert-Butoxycarbonyl)amino]methyl]-1H-pyrrolo[2,3-b]pyridine; 1H-Pyrrolo[2,3-b]pyridine-5-methanamine, N-BOC-protected; BOC-7-Aza-1H-indol-5-ylmethylamine; 5-(Boc-aminomethyl)-7-azaindole; 5-(Boc-aminomethyl)-1H-pyrrolo[2,3-b]pyridine; N-Boc-5-aminomethyl-7-azaindole; 5-(N-Boc-aminomethyl)-1H-pyrrolo[2,3-b]pyridine
EINECS	Contact for details

Quality Control

Our (1H-Pyrrolo[2,3-B]Pyridin-5-Ylmethyl)-Carbamic Acid tert-Butyl Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to cGMP principles where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. Keep the container tightly sealed in a desiccated environment when not in use.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.