Description

(3R)-(4-Fluorophenoxy)-Pyrrolidine Hydrochloride is a high-purity chiral building block and pharmaceutical intermediate of significant importance in modern synthetic chemistry. Its value lies in its defined stereochemistry and functionalized pyrrolidine core, which are critical for constructing complex molecules with specific biological activity. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and other therapeutic agents.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel drug candidates.
• Asymmetric Synthesis: Used as a building block for constructing complex, stereochemically defined molecules in medicinal chemistry.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands or organocatalysts used in enantioselective transformations.
• Chemical Biology Research: Employed in the synthesis of probes and tool compounds for studying biological targets and pathways.
• Process Chemistry & Scale-up: Utilized in the optimization and pilot-scale production of potential therapeutic compounds.
• Academic Research: Used in university and institutional labs for methodological studies in organic and heterocyclic chemistry.

Basic Information

Product Name	(3R)-(4-Fluorophenoxy)-Pyrrolidine Hydrochloride
CAS No.	900512-41-6
Molecular Formula	C10H13FNO•HCl
Molecular Weight	217.68 g/mol (Free base: 181.22 g/mol)
Synonyms	(R)-3-(4-Fluorophenoxy)pyrrolidine hydrochloride; (3R)-3-(4-Fluorophenoxy)-1-azabicyclo[3.3.0]octane hydrochloride; (R)-3-(p-Fluorophenoxy)pyrrolidine HCl; 900512-41-6; (R)-Pyrrolidin-3-yl 4-fluorophenyl ether hydrochloride
EINECS	Contact for details

Quality Control

Every batch of (3R)-(4-Fluorophenoxy)-Pyrrolidine Hydrochloride is manufactured under controlled conditions and undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our quality assurance protocols are designed to meet the stringent requirements of pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, chiral purity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (Chiral HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.