Description

(R)-3-(2-Chlorophenoxy)-Pyrrolidine Hcl is a high-purity chiral building block and pharmaceutical intermediate. This compound is critical for the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs) and other fine chemicals where stereochemistry is paramount. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and development of novel therapeutic agents, particularly in central nervous system (CNS) and cardiovascular drug candidates.
• Asymmetric Synthesis: Used as a precursor or ligand in catalytic asymmetric reactions to induce chirality in target molecules.
• Agrochemical Research: Serves as a building block for developing advanced, enantiopure pesticides and herbicides with improved efficacy and environmental profiles.
• Chemical Biology & Proteomics: Employed in the design and synthesis of molecular probes and enzyme inhibitors for biochemical research.
• Process Chemistry & Scale-up: Supplied for process optimization and pilot-scale manufacturing of chiral compounds under GMP or non-GMP conditions.
• Academic & Contract Research: Essential for synthetic organic chemistry research in academic laboratories and contract research organizations (CROs).

Basic Information

Product Name	(R)-3-(2-Chlorophenoxy)-Pyrrolidine Hydrochloride
CAS No.	900512-34-7
Molecular Formula	C10H13Cl2NO
Molecular Weight	234.12 g/mol
Synonyms	(R)-3-(2-Chlorophenoxy)pyrrolidine hydrochloride; (R)-3-(2-Chlorophenoxy)-1-pyrrolidine hydrochloride; (R)-3-(2-Chlorophenoxy)pyrrolidine HCl; (R)-3-(o-Chlorophenoxy)pyrrolidine hydrochloride; Pyrrolidine, 3-(2-chlorophenoxy)-, hydrochloride, (3R)-; (3R)-3-(2-Chlorophenoxy)pyrrolidine hydrochloride; (R)-(-)-3-(2-Chlorophenoxy)pyrrolidine hydrochloride
EINECS	Contact for details

Quality Control

Every batch of (R)-3-(2-Chlorophenoxy)-Pyrrolidine Hcl is produced and tested under strict quality management systems. We provide comprehensive analytical data to ensure identity, purity, and enantiomeric excess meet the stringent requirements of our clients. A detailed Certificate of Analysis (COA) including chiral purity (HPLC), assay, and impurity profile is available for each lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.