Description

3-(3-Fluorophenoxy)-3-Methyl-Azetidine Hydrochloride is a high-purity, fluorinated azetidine derivative supplied as a hydrochloride salt. This compound is a critical pharmaceutical intermediate valued for its role in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and metabolic disorder research. It is primarily utilized by research institutions, contract research organizations (CROs), and pharmaceutical companies engaged in medicinal chemistry and process development.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, especially those targeting neurological receptors.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs due to its fluorinated phenoxy and azetidine motifs.
• Process Chemistry & Scale-Up: Serves as a starting material or intermediate in the development and optimization of scalable API synthesis routes under GMP conditions.
• Biochemical Research: Potential use as a tool compound or ligand in biochemical assays and target validation studies.
• Custom Synthesis: A versatile substrate for further chemical modifications to create proprietary chemical libraries for high-throughput screening.

Basic Information

Product Name	3-(3-Fluorophenoxy)-3-Methyl-Azetidine Hydrochloride
CAS No.	900511-76-4
Molecular Formula	C10H13FNO • HCl
Molecular Weight	217.67 g/mol (Free base: 181.21 g/mol)
Synonyms	3-Methyl-3-(3-fluorophenoxy)azetidine hydrochloride; 3-(3-Fluorophenoxy)-3-methylazetidine HCl; 1-Azetidine, 3-(3-fluorophenoxy)-3-methyl-, hydrochloride; 3-Methyl-3-(m-fluorophenoxy)azetidine hydrochloride; Azetidine, 3-(3-fluorophenoxy)-3-methyl-, hydrochloride
EINECS	Contact for details

Quality Control

Our 3-(3-Fluorophenoxy)-3-Methyl-Azetidine Hydrochloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing identity, purity, and impurity profiles. Our quality systems are designed to support GMP-grade production upon request for advanced pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure containers are sealed tightly after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.