Description

tert-Butyl 4-Amino-2-Fluorobenzylcarbamate CAS NO 900174-92-7 is a high-purity, fluorinated aromatic amine derivative protected by a Boc (tert-butoxycarbonyl) group. This compound serves as a critical pharmaceutical intermediate and building block in organic synthesis, enabling the controlled introduction of functionalized benzylamine motifs. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the research and development of advanced herbicides and pesticides, leveraging the fluorine atom for enhanced biological activity and metabolic stability.
• Peptide Mimetics & PROTACs: Serves as a versatile scaffold for constructing peptide-like molecules and Proteolysis Targeting Chimeras (PROTACs) due to its protected amine functionality.
• Material Science Research: Employed in the development of specialty polymers, liquid crystals, and organic electronic materials where fluorinated aromatic structures are beneficial.
• Chemical Biology Probes: Acts as a precursor for fluorescent tags, affinity labels, and other molecular probes used in biochemical and diagnostic research.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis projects and scale-up production under cGMP or ISO standards.

Basic Information

Product Name	tert-Butyl 4-Amino-2-Fluorobenzylcarbamate
CAS No.	900174-92-7
Molecular Formula	C12H17FN2O2
Molecular Weight	240.28 g/mol
Synonyms	tert-Butyl N-[(4-Amino-2-fluorophenyl)methyl]carbamate; Boc-4-Amino-2-fluorobenzylamine; N-Boc-4-Amino-2-fluorobenzylamine; 2-Fluoro-4-aminobenzylcarbamic acid tert-butyl ester; tert-Butyl (4-amino-2-fluorobenzyl)carbamate; 4-Amino-2-fluorobenzylamine Boc-protected; Boc-A2FBA; 900174-92-7
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-Amino-2-Fluorobenzylcarbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and MS, to ensure it meets the high standards required for pharmaceutical R&D and production. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.