Description

3-[4-Chloro-3-(Trifluoromethyl)Phenyl]Propionic Acid is a high-value fluorinated aromatic building block essential for advanced organic synthesis. This compound matters for its unique molecular structure, combining a propionic acid moiety with chloro and trifluoromethyl substituents, which imparts specific electronic and steric properties critical for modulating bioactivity and material characteristics. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for non-steroidal anti-inflammatory drugs (NSAIDs) and other bioactive molecules.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and pesticides, where the trifluoromethyl group enhances lipophilicity and metabolic stability.
• Liquid Crystal & OLED Material Precursor: Serves as a building block for fluorinated aromatic components in electronic display and lighting materials.
• Polymer Modification: Incorporated as a monomer or modifier to introduce specific functional groups into polymer chains, altering physical properties.
• Chemical Research & Development: A versatile reagent for exploring novel organic reactions and creating compound libraries for screening.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for bespoke chemical synthesis projects.

Basic Information

Product Name	3-[4-Chloro-3-(Trifluoromethyl)Phenyl]Propionic Acid
CAS No.	900027-15-8
Molecular Formula	C10H8ClF3O2
Molecular Weight	252.62 g/mol
Synonyms	4-Chloro-3-(trifluoromethyl)hydrocinnamic acid; 3-(4-Chloro-3-(trifluoromethyl)phenyl)propanoic acid; 3-(4-Chloro-alpha,alpha,α-trifluoro-m-tolyl)propionic Acid; 2-[4-Chloro-3-(trifluoromethyl)phenyl]ethanecarboxylic acid; 900027-15-8; 3-(4-Chloro-3-trifluoromethylphenyl)propionic acid
EINECS	Contact for details

Quality Control

Our 3-[4-Chloro-3-(Trifluoromethyl)Phenyl]Propionic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles where applicable, ensuring reliability for your critical research and development processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases, oxidizing agents, and sources of ignition. Due to its nature as a strong acid/organic solvent, handle with appropriate personal protective equipment in a fume hood or well-ventilated area.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.