Description

5-Methoxy-3-[(E)-2-(3-Methyl-4-Nitro-5-Isoxazolyl)Ethenyl]-1H-Indole is a sophisticated heterocyclic compound featuring a unique indole-isoxazole hybrid structure, making it a valuable advanced intermediate for pharmaceutical research and development. Its molecular architecture is specifically designed to serve as a key building block in the synthesis of novel bioactive molecules, particularly those targeting complex biological pathways. This compound is of primary interest to medicinal chemists and R&D departments in the pharmaceutical and biotechnology industries engaged in developing new therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and anti-inflammatory targets.
• Medicinal Chemistry Research: Used as a scaffold for structure-activity relationship (SAR) studies to optimize potency and selectivity of lead compounds.
• Biochemical Probe Development: Utilized in the design and creation of molecular probes for studying enzyme function and receptor interactions.
• High-Throughput Screening (HTS): Employed as a component in compound libraries for screening against novel biological targets.
• Organic Synthesis Building Block: Acts as a versatile intermediate for constructing more complex polycyclic heterocyclic systems.
• Agrochemical Research: Investigated as a potential intermediate for developing new crop protection agents with novel modes of action.

Basic Information

Product Name	5-Methoxy-3-[(E)-2-(3-Methyl-4-Nitro-5-Isoxazolyl)Ethenyl]-1H-Indole
CAS No.	900015-42-1
Molecular Formula	C₁₅H₁₃N₃O₄
Molecular Weight	299.28 g/mol
Synonyms	5-Methoxy-3-[(E)-2-(3-methyl-4-nitro-5-isoxazolyl)ethenyl]-1H-indole; 1H-Indole, 5-methoxy-3-[(E)-2-(3-methyl-4-nitro-5-isoxazolyl)ethenyl]-; (E)-5-Methoxy-3-(2-(3-methyl-4-nitroisoxazol-5-yl)vinyl)-1H-indole; 5-Methoxy-3-[(E)-2-(3-methyl-4-nitro-1,2-oxazol-5-yl)ethenyl]-1H-indole; Indole-isoxazole hybrid; 900015-42-1
EINECS	Contact for details

Quality Control

Our production of 5-Methoxy-3-[(E)-2-(3-Methyl-4-Nitro-5-Isoxazolyl)Ethenyl]-1H-Indole adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity, essential for sensitive R&D applications. All material is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment to support your quality and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.