Description

1-(4-Fluorobenzyl)-1H-Benzo[D]Imidazole-2-Thiol is a high-purity, advanced pharmaceutical intermediate characterized by its unique benzimidazole-thiol core functionalized with a fluorobenzyl group. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular interactions. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new drug candidates and crop protection agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential antiviral, anticancer, and anti-inflammatory drug candidates.
• Agrochemical Research: Used in the development of new fungicides and pesticides, leveraging the bioactivity of the benzimidazole moiety.
• Chemical Synthesis: Serves as a versatile precursor for creating more complex heterocyclic compounds in medicinal chemistry.
• Biochemical Research: Employed as a ligand or inhibitor in enzymatic studies and proteomics research.
• Material Science: Investigated for use in the development of specialty polymers and organic electronic materials.

Basic Information

Product Name	1-(4-Fluorobenzyl)-1H-Benzo[D]Imidazole-2-Thiol
CAS No.	99960-22-2
Molecular Formula	C₁₄H₁₁FN₂S
Molecular Weight	258.31 g/mol
Synonyms	1-[(4-Fluorophenyl)methyl]-1H-benzimidazole-2-thiol; 1-(4-Fluorobenzyl)-2-mercaptobenzimidazole; 1-(4-Fluorobenzyl)-2-benzimidazolethiol; 2-Mercapto-1-(4-fluorobenzyl)benzimidazole; 1H-Benzimidazole-2-thiol, 1-[(4-fluorophenyl)methyl]-; 99960-22-2; 1-(p-Fluorobenzyl)benzimidazole-2-thiol
EINECS	Contact for details

Quality Control

Our 1-(4-Fluorobenzyl)-1H-Benzo[D]Imidazole-2-Thiol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure compliance with exacting standards for pharmaceutical intermediates. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.