Description

(4As)-3,4,4Aα,5,6,7,8,8Aα-Octahydro-5α-Methyl-8β-Isopropenylnaphthalene-2-Carboxylic Acid CAS NO 99957-14-9 is a complex, high-purity decalin-based carboxylic acid derivative with a defined stereochemistry. This compound matters as a critical chiral intermediate in advanced organic synthesis, offering a rigid, functionalized scaffold for constructing complex molecules. It is primarily needed by pharmaceutical R&D and fine chemical manufacturers for the development of novel active pharmaceutical ingredients (APIs) and specialty agrochemicals.

Application

• Pharmaceutical Intermediate: Serves as a key chiral building block in the synthesis of steroids, terpenoids, and other complex bioactive molecules.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, leveraging its unique polycyclic structure.
• Fine Chemical Production: Acts as a precursor for fragrances, flavors, and other high-value specialty chemicals requiring specific stereochemistry.
• Academic & Industrial Research: Employed in methodological studies and process chemistry for asymmetric synthesis and catalyst development.
• Material Science Precursor: Investigated for the synthesis of specialized polymers or liquid crystals with tailored properties.

Basic Information

Product Name	(4As)-3,4,4Aα,5,6,7,8,8Aα-Octahydro-5α-Methyl-8β-Isopropenylnaphthalene-2-Carboxylic Acid
CAS No.	99957-14-9
Molecular Formula	C₁₅H₂₂O₂
Molecular Weight	234.33 g/mol
Synonyms	5α-Methyl-8β-isopropenylperhydronaphthalene-2-carboxylic Acid; (4aR,5S,8aS)-5-Methyl-8-(prop-1-en-2-yl)-1,2,3,4,4a,5,6,7,8,8a-decahydronaphthalene-2-carboxylic Acid; Decahydro-5-methyl-8-(1-methylethenyl)-2-naphthalenecarboxylic Acid; (4aS,5R,8aR)-5-Methyl-8-(prop-1-en-2-yl)decahydro-2-naphthoic Acid; 99957-14-9; A key intermediate for abietic acid-type diterpenes.
EINECS	Contact for details

Quality Control

Our (4As)-3,4,4Aα,5,6,7,8,8Aα-Octahydro-5α-Methyl-8β-Isopropenylnaphthalene-2-Carboxylic Acid is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure it meets the high standards required for pharmaceutical and fine chemical applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound may be sensitive to prolonged exposure to air and moisture; therefore, it is recommended to store under an inert atmosphere for long-term preservation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.