Description

1-(4-Amino-Benzenesulfonyl)-Pyrrolidine-2-Carboxylic Acid is a high-purity sulfonamide derivative and a key synthetic intermediate in advanced organic chemistry. Its molecular structure, featuring both a sulfonamide group and a carboxylic acid moiety, makes it a versatile building block for constructing complex pharmacologically active molecules. This compound is primarily sought after by research institutions and pharmaceutical development companies engaged in the synthesis of novel drug candidates and fine chemicals.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of potential therapeutic agents, particularly those targeting enzyme inhibition.
• Protease Inhibitor Research: Used in the development of inhibitors for various proteases, leveraging its sulfonamide pharmacophore.
• Chemical Biology & Medicinal Chemistry: Serves as a scaffold or building block for creating compound libraries in drug discovery programs.
• Fine Chemical Synthesis: Employed in multi-step organic syntheses to introduce specific functional groups into target molecules.
• Bioconjugation Chemistry: The carboxylic acid group allows for coupling reactions, useful in creating labeled compounds or probes.

Basic Information

Product Name	1-(4-Amino-Benzenesulfonyl)-Pyrrolidine-2-Carboxylic Acid
CAS No.	99945-07-0
Molecular Formula	C11H14N2O4S
Molecular Weight	270.31 g/mol
Synonyms	4-Amino-N-(2-carboxypyrrolidin-1-yl)benzenesulfonamide; L-Proline, 1-[(4-aminophenyl)sulfonyl]-; 1-[(4-Aminophenyl)sulfonyl]pyrrolidine-2-carboxylic Acid; 1-(4-Aminosulfonylphenyl)pyrrolidine-2-carboxylic Acid; 4-Amino-benzenesulfonic acid pyrrolidine-2-carboxylic acid amide; ABPC; (S)-1-(4-Aminobenzenesulfonyl)pyrrolidine-2-carboxylic Acid
EINECS	Contact for details

Quality Control

Our 1-(4-Amino-Benzenesulfonyl)-Pyrrolidine-2-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and development applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed and away from direct light to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.