Description

H-Tyr-Gly-Nh2 Hcl is a protected dipeptide building block, specifically the hydrochloride salt of H-Tyr-Gly-NH₂. This compound is a crucial intermediate in solid-phase peptide synthesis (SPPS), enabling the controlled construction of complex peptide sequences. It is primarily utilized by research institutions and pharmaceutical companies engaged in peptide drug discovery, development, and production.

Application

• Peptide Synthesis Intermediate: A fundamental building block for the chemical synthesis of longer, biologically active peptide chains in both research and commercial scales.
• Pharmaceutical Research: Used in the discovery and development of novel therapeutic peptides targeting various diseases.
• Biochemical Research: Serves as a standard or reagent in studies of enzyme kinetics, receptor-ligand interactions, and metabolic pathways.
• Cosmetic Peptide Development: Incorporated into the R&D of bioactive peptides for skincare and cosmetic formulations.
• Academic Research: Employed in university and institutional labs for teaching and fundamental research in organic chemistry and biochemistry.

Basic Information

Product Name	H-Tyr-Gly-Nh2 Hcl
CAS No.	99940-62-2
Molecular Formula	C₁₁H₁₆N₃O₄ • HCl
Molecular Weight	289.72 g/mol (Free base: 254.27 g/mol)
Synonyms	H-Tyr-Gly-NH₂ hydrochloride; N-(tert-Butoxycarbonyl)-O-benzyl-L-tyrosylglycinamide hydrochloride; Boc-Tyr(Bzl)-Gly-NH₂ • HCl; L-Tyrosylglycinamide hydrochloride; Tyr-Gly amide hydrochloride; Fmoc-Tyr(tBu)-Gly-NH₂ • HCl (related protected form); Peptide building block 99940-62-2
EINECS	Contact for details

Quality Control

Our H-Tyr-Gly-Nh2 Hcl is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC for purity, chiral analysis for enantiomeric purity, and NMR/IR for structural confirmation. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or cGMP guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C for long-term stability. This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a desiccated environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.