Description

2-Amino-1,2,3,4-Tetrahydro-5,8-Dimethoxy-2-Naphthalenecarboxylic Acid is a specialized tetrahydro-naphthalene derivative, serving as a critical chiral building block and advanced pharmaceutical intermediate. Its value lies in its unique fused-ring structure and functional groups, which are essential for constructing complex molecules in medicinal chemistry. This compound is primarily needed by research institutions and pharmaceutical manufacturers focused on developing novel therapeutic agents, particularly in the areas of central nervous system (CNS) and cardiovascular drug discovery.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of complex active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used in the discovery and development of new drug candidates, especially for neurological and cardiovascular targets.
• Asymmetric Synthesis: Employed as a building block in stereoselective reactions to create enantiomerically pure compounds.
• Chemical Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical labs.
• Organic Synthesis: A versatile precursor for synthesizing other functionalized tetralin and naphthalene derivatives.

Basic Information

Product Name	2-Amino-1,2,3,4-Tetrahydro-5,8-Dimethoxy-2-Naphthalenecarboxylic Acid
CAS No.	99907-84-3
Molecular Formula	C₁₃H₁₇NO₄
Molecular Weight	251.28 g/mol
Synonyms	5,8-Dimethoxy-1,2,3,4-tetrahydro-2-naphthoic acid, 2-amino-; 2-Amino-5,8-dimethoxy-1,2,3,4-tetrahydronaphthalene-2-carboxylic acid; 2-Aminotetralin-2-carboxylic acid derivative; ATDN; (2-Amino-5,8-dimethoxy-1,2,3,4-tetrahydro-2-naphthyl)carboxylic acid; 2-Amino-1,2,3,4-tetrahydro-5,8-dimethoxy-2-naphthoic acid
EINECS	Contact for details

Quality Control

Our 2-Amino-1,2,3,4-Tetrahydro-5,8-Dimethoxy-2-Naphthalenecarboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral purity assessment, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.