Description

(R)-2-Hydroxy-4-Phenylbutanamide is a chiral, non-proteinogenic amino acid derivative of significant interest in advanced organic synthesis. This compound serves as a crucial chiral building block and intermediate for the development of pharmaceuticals and bioactive molecules. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for creating enantiomerically pure compounds.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of enzyme inhibitors, receptor antagonists, and other active pharmaceutical ingredients (APIs).
• Agrochemical Research: Building block for developing novel, enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Peptidomimetics: Used in the design and synthesis of peptide analogs and mimetics for drug discovery programs.
• Asymmetric Synthesis: Employed as a chiral auxiliary or starting material in stereoselective chemical reactions to introduce the (R)-configuration.
• Biochemical Research: Serves as a substrate or inhibitor in enzymatic studies and metabolic pathway investigations.
• Fine Chemical Production: Intermediate for manufacturing specialty chemicals, flavors, and fragrances requiring high optical purity.

Basic Information

Product Name	(R)-2-Hydroxy-4-Phenylbutanamide
CAS No.	99902-36-0
Molecular Formula	C10H13NO2
Molecular Weight	179.22 g/mol
Synonyms	(R)-2-Hydroxy-4-phenylbutyramide; (R)-HOPA; D-2-Hydroxy-4-phenylbutanamide; (2R)-2-Hydroxy-4-phenylbutanamide; (R)-α-Hydroxy-γ-phenylbutyramide; (R)-2-Hydroxy-4-phenylbutyric acid amide; (R)-HPBA; γ-Phenyl-(R)-2-hydroxybutyramide
EINECS	Contact for details

Quality Control

Our (R)-2-Hydroxy-4-Phenylbutanamide is produced under strict quality management systems. Each batch is characterized and tested to ensure identity, purity, and enantiomeric excess meet the stringent requirements for research and development applications. Comprehensive analytical methods including HPLC, chiral chromatography, and NMR are employed. A Certificate of Analysis (COA) detailing specific results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.