Description

(2S)-2,3-Dihydro-5-Hydroxy-8,8-Dimethyl-2α-Phenyl-6-(3-Methyl-2-Butenyl)-4H,8H-Benzo[1,2-B:3,4-B']Dipyran-4-One is a high-purity, complex organic compound belonging to the benzodipyranone class, valued for its specific stereochemistry and functional groups. This compound is a critical advanced pharmaceutical intermediate and a valuable scaffold in medicinal chemistry research for developing novel therapeutic agents. It is primarily sought by pharmaceutical R&D and fine chemical synthesis sectors for its role in creating molecules with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, particularly in oncology and anti-inflammatory research.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Organic Synthesis: Employed in advanced organic synthesis for constructing complex natural product analogs and heterocyclic compounds.
• Biochemical Research: Investigated for its potential biological activity and interaction with specific enzymes or receptors in biochemical assays.

Basic Information

Product Name	(2S)-2,3-Dihydro-5-Hydroxy-8,8-Dimethyl-2α-Phenyl-6-(3-Methyl-2-Butenyl)-4H,8H-Benzo[1,2-B:3,4-B']Dipyran-4-One
CAS No.	99877-71-1
Molecular Formula	C25H26O4
Molecular Weight	390.47 g/mol
Synonyms	5-Hydroxy-8,8-dimethyl-2α-phenyl-6-(3-methyl-2-butenyl)-2,3-dihydro-4H,8H-benzo[1,2-b:3,4-b']dipyran-4-one; (2S)-form of the above; Benzodipyran-4-one derivative; Sophoraflavanone G isomer (related compound); Flavonoid-derived intermediate
EINECS	Contact for details

Quality Control

Our (2S)-2,3-Dihydro-5-Hydroxy-8,8-Dimethyl-2α-Phenyl-6-(3-Methyl-2-Butenyl)-4H,8H-Benzo[1,2-B:3,4-B']Dipyran-4-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral analysis to confirm stereochemical integrity, ensuring compliance with research-grade specifications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); therefore, containers should be kept sealed under an inert atmosphere if necessary to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 97.0%
Chiral Purity	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.2%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.