Description

Ethyl N,N`-Di(Boc)-L-Lysine is a protected derivative of the essential amino acid L-Lysine, featuring two tert-butoxycarbonyl (Boc) groups and an ethyl ester. This compound is a crucial building block in solid-phase peptide synthesis (SPPS), where it provides orthogonal protection for the lysine side chain amine, enabling the controlled construction of complex peptides. It is primarily utilized by pharmaceutical researchers, biotech companies, and fine chemical manufacturers developing therapeutic peptides, diagnostic agents, and novel biomaterials.

Application

• Peptide Synthesis Intermediate: A key protected amino acid derivative for the synthesis of lysine-containing peptides in pharmaceutical research and development.
• Solid-Phase Peptide Synthesis (SPPS): Serves as a critical building block, allowing for the sequential addition of amino acids with selective deprotection strategies.
• Therapeutic Peptide Production: Used in the manufacture of peptide-based drugs targeting metabolic disorders, oncology, and cardiovascular diseases.
• Bioconjugation and Labeling: The protected amine groups allow for specific chemical modifications, useful in creating antibody-drug conjugates (ADCs) or fluorescent probes.
• Research & Development: Employed in academic and industrial labs for exploring new peptide structures and their biological activities.
• Custom Synthesis Services: A fundamental reagent for contract research and manufacturing organizations (CROs/CMOs) offering bespoke peptide production.

Basic Information

Product Name	Ethyl N,N`-Di(Boc)-L-Lysine
CAS No.	99872-16-9
Molecular Formula	C20H38N2O6
Molecular Weight	402.53 g/mol
Synonyms	Nα,Nε-Bis(tert-butoxycarbonyl)-L-lysine ethyl ester; Nα,Nε-Di-Boc-L-lysine ethyl ester; H-Lys(Boc)-Boc-OEt; Ethyl N2,N6-bis[(tert-butoxy)carbonyl]-L-lysinate; Boc-Lys(Boc)-OEt; L-Lysine, N2,N6-bis[(1,1-dimethylethoxy)carbonyl]-, ethyl ester; Di-Boc-L-lysine-OEt
EINECS	Contact for details

Quality Control

Our Ethyl N,N`-Di(Boc)-L-Lysine is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity, suitable for demanding research and cGMP applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards and can support regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. Keep container tightly sealed in a desiccated environment when not in use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥98.0%
Optical Rotation [α]D20	Contact for details
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.