Description

2-Cyclopropyl-2-Hydroxy-Propionic Acid is a versatile chiral building block and intermediate of significant interest in advanced organic synthesis. Its unique structure, featuring both a cyclopropyl ring and a hydroxylated carboxylic acid moiety, makes it a valuable precursor for creating complex molecules with specific stereochemistry. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to synthesize novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of active pharmaceutical ingredients (APIs), particularly in antiviral, anti-inflammatory, and central nervous system (CNS) drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the cyclopropyl group can impart specific biological activity and stability.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis to control stereoselectivity.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances requiring high-purity, structurally complex intermediates.
• Academic and Industrial R&D: A valuable compound for methodological studies in organic chemistry, including ring-opening reactions and stereocontrolled transformations.

Basic Information

Product Name	2-Cyclopropyl-2-Hydroxy-Propionic Acid
CAS No.	99848-37-0
Molecular Formula	C6H10O3
Molecular Weight	130.14 g/mol
Synonyms	2-Hydroxy-2-cyclopropylpropanoic Acid; α-Cyclopropyl-α-hydroxypropionic Acid; 2-Cyclopropyl-2-hydroxypropanoic Acid; (RS)-2-Cyclopropyl-2-hydroxypropionic Acid; DL-2-Cyclopropyl-2-hydroxypropionic Acid; Cyclopropanecarboxylic acid, 1-hydroxy-1-methylethyl ester (tautomer); 2-Cyclopropyl lactic acid
EINECS	Contact for details

Quality Control

We maintain stringent quality control protocols for our chemical intermediates. Production follows current Good Manufacturing Practice (cGMP) principles where applicable, and every batch is analyzed to ensure it meets precise specifications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to guarantee traceability and consistency for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and heat sources.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Specific Rotation	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.