Description

Z-Gpa-Na is a high-purity, protected amino acid derivative widely utilized in peptide synthesis and pharmaceutical research. This compound serves as a critical building block for the controlled introduction of glutamic acid residues, enabling the creation of complex peptides with specific biological activities. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors who require reliable, high-quality intermediates for advanced drug discovery and development projects.

Application

• Solid-Phase Peptide Synthesis (SPPS): As a key protected glutamic acid precursor for the sequential assembly of peptide chains.
• Solution-Phase Peptide Synthesis: Used in the synthesis of complex peptide fragments and small proteins.
• Pharmaceutical Intermediate: A vital raw material in the research and production of peptide-based therapeutics and active pharmaceutical ingredients (APIs).
• Bioconjugation: Employed in the modification of proteins and other biomolecules to attach functional groups or labels.
• Chemical Biology Research: Used in the study of enzyme mechanisms, receptor-ligand interactions, and the development of novel biochemical probes.
• Fine Chemical Synthesis: Serves as a chiral synthon for the preparation of non-peptide compounds with glutamic acid-like structures.

Basic Information

Product Name	Z-Gpa-Na
CAS No.	99795-08-1
Molecular Formula	C14H16NNaO6
Molecular Weight	317.27 g/mol
Synonyms	Sodium (benzyloxycarbonyl)-L-glutaminate; Z-L-Glutamic acid α-benzyl ester sodium salt; N-Carbobenzoxy-L-glutamic acid α-benzyl ester sodium salt; N-Cbz-L-glutamic acid α-benzyl ester sodium salt; (S)-2-(((Benzyloxy)carbonyl)amino)pentanedioic acid 1-benzyl ester sodium salt; Z-Glu(OBzl)-ONa; Z-Glu-OBzl sodium salt; L-Glutamic acid, N-[(phenylmethoxy)carbonyl]-, 1-(phenylmethyl) ester, sodium salt (1:1)
EINECS	Contact for details

Quality Control

Our Z-Gpa-Na is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for purity and chiral analysis to confirm enantiomeric integrity. Certificates of Analysis (COA) detailing all specifications are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to prevent exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Optical Rotation [α]20/D	-15.0° to -18.0° (c=1 in DMF)
Water Content (KF)	≤ 2.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.