Description

4-Bromo-1-Methanesulfonyl-2-Methylbenzene is a high-purity organic intermediate characterized by its bromine and methanesulfonyl functional groups. This compound is valued for its role as a versatile building block in advanced organic synthesis, enabling the construction of complex molecular architectures. It is primarily sought by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and fungicides, where its structural motifs contribute to biological activity.
• Material Science Research: Serves as a monomer or functionalization agent in the development of specialty polymers and liquid crystals.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form biaryl structures.
• Sulfone Chemistry Exploration: Utilized in academic and industrial R&D to study sulfone group reactivity and its application in medicinal chemistry.

Basic Information

Product Name	4-Bromo-1-Methanesulfonyl-2-Methylbenzene
CAS No.	99768-21-5
Molecular Formula	C8H9BrO2S
Molecular Weight	249.13 g/mol
Synonyms	1-Bromo-4-(methylsulfonyl)-2-methylbenzene; 2-Methyl-4-bromophenyl methyl sulfone; 4-Bromo-2-methylphenyl methyl sulfone; 4-Bromo-α,α-dimethylbenzenemethanesulfonic acid; Methyl 4-bromo-2-methylphenyl sulfone; p-Bromo-o-tolyl methyl sulfone
EINECS	Contact for details

Quality Control

Our 4-Bromo-1-Methanesulfonyl-2-Methylbenzene is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent quality suitable for sensitive synthetic applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.