Description

[2S-[1[R*(R*)],2α,3Aβ,6Aβ]]-1-[2-[[3-Cyclohexyl-1-(Ethoxycarbonyl)Propyl]Amino]-1-Oxoprop is a complex, stereochemically defined organic compound featuring a cyclohexyl and ethoxycarbonyl functional groups. This compound serves as a critical chiral intermediate or building block in advanced organic synthesis, where precise molecular architecture is paramount. It is primarily required by pharmaceutical R&D and fine chemical manufacturers for the development of novel active pharmaceutical ingredients (APIs) and other high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the multi-step synthesis of complex drug molecules, particularly those targeting neurological or metabolic pathways.
• Peptidomimetic Research: Used in the design and synthesis of peptide analogs and enzyme inhibitors due to its structural similarity to amino acid derivatives.
• Asymmetric Catalysis Ligand Precursor: Serves as a starting material for synthesizing specialized ligands used in asymmetric hydrogenation or carbon-carbon bond forming reactions.
• Fine Chemical Synthesis: Employed in the production of high-purity, specialty chemicals for agrochemicals and advanced material science applications.
• Academic & Industrial R&D: A valuable compound for methodological development in organic chemistry and for exploring new synthetic routes.

Basic Information

Product Name	[2S-[1[R*(R*)],2α,3Aβ,6Aβ]]-1-[2-[[3-Cyclohexyl-1-(Ethoxycarbonyl)Propyl]Amino]-1-Oxoprop
CAS No.	99742-35-5
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	(2S,3aS,6aS)-1-[(2S)-2-[[(1S)-3-Cyclohexyl-1-(ethoxycarbonyl)propyl]amino]propanoyl]octahydrocyclopenta[b]pyrrole-2-carboxylic acid; 1-[(2S)-2-[[(1S)-3-Cyclohexyl-1-(ethoxycarbonyl)propyl]amino]propanoyl]- (2S,3aS,6aS)-octahydrocyclopenta[b]pyrrole-2-carboxylic acid; Cyclohexyl-ethoxycarbonyl propyl amino oxoprop derivative; Perindopril intermediate; ACE inhibitor intermediate; Stereoisomer of perindoprilat precursor.
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We implement strict in-process controls and final release testing, which typically includes chiral purity analysis, identity confirmation, and impurity profiling. Certificates of Analysis (COA) detailing batch-specific results are available upon request. Production can be aligned with cGMP guidelines for pharmaceutical applications upon requirement.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single unknown impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.