Description

(S)-Methyl 5-Oxo-1-((R)-1-Phenylethyl)Pyrrolidine-3-Carboxylate CAS NO 99735-46-3 is a high-purity chiral intermediate of significant importance in asymmetric synthesis. This compound is valued for its role as a key building block in the development of active pharmaceutical ingredients (APIs) and other fine chemicals. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for creating enantiomerically pure products.

Application

• Pharmaceutical Intermediate: A critical chiral building block for the synthesis of complex drug molecules, particularly in neurological and cardiovascular therapeutic areas.
• Asymmetric Synthesis Catalyst/Precursor: Used in the preparation of chiral ligands and organocatalysts for enantioselective transformations.
• Agrochemical Research: Serves as a precursor for developing novel, enantiomerically pure pesticides and herbicides.
• Academic & Process Chemistry: A valuable reagent for methodological development in organic synthesis and scale-up process optimization.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals requiring high stereochemical fidelity.

Basic Information

Product Name	(S)-Methyl 5-Oxo-1-((R)-1-Phenylethyl)Pyrrolidine-3-Carboxylate
CAS No.	99735-46-3
Molecular Formula	C15H19NO3
Molecular Weight	261.32 g/mol
Synonyms	(3S)-1-[(1R)-1-Phenylethyl]-5-oxopyrrolidine-3-carboxylic acid methyl ester; Methyl (3S)-1-[(1R)-1-phenylethyl]-5-oxo-3-pyrrolidinecarboxylate; (S)-Methyl 5-oxo-1-((R)-1-phenylethyl)pyrrolidine-3-carboxylate; (S)-Methyl 1-((R)-1-phenylethyl)-5-oxopyrrolidine-3-carboxylate; 99735-46-3; Chiral pyrrolidinone derivative
EINECS	Contact for details

Quality Control

Our (S)-Methyl 5-Oxo-1-((R)-1-Phenylethyl)Pyrrolidine-3-Carboxylate is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC and NMR, to ensure high enantiomeric excess (ee) and chemical purity suitable for advanced synthetic applications. Certificates of Analysis (COA) with full characterization data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. Keep the container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.