Description

Methyl (3R)-5-Oxo-1-[(1S)-1-Phenylethyl]Pyrrolidine-3-Carboxylate is a high-purity, chiral pyrrolidine derivative serving as a critical building block in advanced organic synthesis. This compound is valued for its defined stereochemistry, which is essential for imparting specific biological activity and physical properties in final target molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) and metabolic disorder targets.
• Asymmetric Synthesis: Employed as a precursor or catalyst ligand in stereoselective reactions to construct complex molecular architectures.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes due to its versatile functional groups.
• Fine Chemical Production: Serves as a building block for the synthesis of specialty chemicals, agrochemicals, and advanced materials requiring specific chiral centers.
• Academic & R&D Laboratories: Utilized in methodological development and as a reference standard in chiral analysis and separation science.

Basic Information

Product Name	Methyl (3R)-5-Oxo-1-[(1S)-1-Phenylethyl]Pyrrolidine-3-Carboxylate
CAS No.	99724-15-9
Molecular Formula	C14H17NO3
Molecular Weight	247.29 g/mol
Synonyms	(3R)-1-[(1S)-1-Phenylethyl]-5-oxopyrrolidine-3-carboxylic acid methyl ester; Methyl (3R)-5-oxo-1-[(1S)-1-phenylethyl]-3-pyrrolidinecarboxylate; (R)-Methyl 5-oxo-1-((S)-1-phenylethyl)pyrrolidine-3-carboxylate; (3R,1'S)-Methyl 1-(1-phenylethyl)-5-oxopyrrolidine-3-carboxylate; Chiral Pyrrolidinone Ester; 99724-15-9; L-Proline derivative
EINECS	Contact for details

Quality Control

Our production of Methyl (3R)-5-Oxo-1-[(1S)-1-Phenylethyl]Pyrrolidine-3-Carboxylate adheres to stringent quality management protocols to ensure batch-to-batch consistency and high chemical purity. Each lot is fully characterized and tested using advanced analytical techniques including HPLC, GC, NMR, and chiral analysis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider inert gas purging to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% e.e.
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.