Description

1-Azabicyclo[3.2.1]octane-7-carboxylic acid (6Ci) is a specialized bicyclic organic compound featuring a carboxylic acid functional group on a bridged nitrogen-containing ring system. This unique structure makes it a valuable advanced pharmaceutical intermediate and a versatile building block for medicinal chemistry research. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active compounds.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of complex drug candidates, particularly those targeting neurological and cardiovascular diseases.
• Medicinal Chemistry Research: Used in high-throughput screening and structure-activity relationship (SAR) studies to develop new pharmacophores.
• Agrochemical Synthesis: Serves as a precursor in the development of novel herbicides and pesticides with specific biological activity.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme mechanisms and biological pathways.
• Ligand and Catalyst Development: The rigid bicyclic framework can be utilized to create novel ligands for asymmetric catalysis.
• Academic Research: Used in universities and research institutes for methodological studies in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	1-Azabicyclo[3.2.1]octane-7-carboxylic acid (6Ci)
CAS No.	99709-35-0
Molecular Formula	C8H13NO2
Molecular Weight	155.19 g/mol
Synonyms	7-Carboxy-1-azabicyclo[3.2.1]octane; 1-Azabicyclo[3.2.1]octane-7-carboxylic acid; 7-(Carboxy)-1-azabicyclo[3.2.1]octane; Tropane-7-carboxylic acid (related skeleton); Endo-7-Carboxy-1-azabicyclo[3.2.1]octane; 1-Azabicyclo[3.2.1]octane-7-carboxylate (anion form); 99709-35-0 (CAS Index Name base); Bicyclic proline analog
EINECS	Contact for details

Quality Control

Our 1-Azabicyclo[3.2.1]octane-7-carboxylic acid is produced under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity and chiral integrity, NMR for structural confirmation, and KF titration for moisture content. A detailed Certificate of Analysis (COA) is provided with each shipment, ensuring traceability and compliance with your research or cGMP starting material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The product may be hygroscopic; keep the container tightly sealed under an inert atmosphere if necessary for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.