Description

1-Piperidinecarboxylic Acid, 4-Formyl-, Ethyl Ester is a versatile and high-value piperidine derivative, serving as a critical chiral building block in advanced organic synthesis. Its core value proposition lies in its reactive formyl and ester functional groups, which enable the construction of complex nitrogen-containing heterocycles and pharmacophores. This compound is essential for research chemists and process development scientists in the pharmaceutical and agrochemical industries, where it is used to develop new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and antiviral therapies.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, leveraging its piperidine scaffold.
• Chiral Ligand & Catalyst Development: Serves as a starting material for creating sophisticated chiral auxiliaries and catalysts used in asymmetric synthesis.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances requiring specific stereochemistry.
• Academic & Industrial R&D: A valuable reagent for methodological studies in organic chemistry and for scaling up novel synthetic routes.
• Peptidomimetic Chemistry: Used to incorporate constrained amino acid analogs into peptide chains to modify biological activity and stability.

Basic Information

Product Name	1-Piperidinecarboxylic Acid, 4-Formyl-, Ethyl Ester
CAS No.	99658-58-9
Molecular Formula	C9H15NO3
Molecular Weight	185.22 g/mol
Synonyms	Ethyl 4-Formylpiperidine-1-carboxylate; 4-Formyl-1-piperidinecarboxylic Acid Ethyl Ester; 1-Carbethoxy-4-formylpiperidine; 4-Formylpiperidine-1-carboxylic Acid Ethyl Ester; NSC 405124; 1-(Ethoxycarbonyl)-4-formylpiperidine; 4-Carbaldehyde-1-piperidinecarboxylic Acid Ethyl Ester
EINECS	Contact for details

Quality Control

Our 1-Piperidinecarboxylic Acid, 4-Formyl-, Ethyl Ester is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and process chemistry. Certificates of Analysis (COA) documenting batch-specific results are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to handle and store the material under an inert atmosphere for long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.