Description

(2S)-2-Amino-4-[[2-Hydroxy-2-(4-Hydroxyphenyl)Ethyl]Carbamoyl]Butanoic Acid is a high-purity chiral amino acid derivative of significant interest in advanced organic synthesis. This compound matters as a sophisticated building block for constructing complex molecules with specific stereochemistry and biological activity. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents, peptide mimetics, and specialized biochemical probes.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for targeted therapies.
• Peptide Chemistry: Used in solid-phase and solution-phase peptide synthesis to introduce a unique tyrosine-like moiety with an extended side chain, enabling structure-activity relationship (SAR) studies.
• Bioconjugation: Serves as a specialized linker or spacer molecule for attaching labels, drugs, or other functional groups to biomolecules in bioconjugation strategies.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes to study enzyme mechanisms, protein-protein interactions, and cellular pathways.
• Asymmetric Synthesis: Acts as a precursor or template in catalytic asymmetric synthesis to create enantiomerically pure compounds for high-value applications.

Basic Information

Product Name	(2S)-2-Amino-4-[[2-Hydroxy-2-(4-Hydroxyphenyl)Ethyl]Carbamoyl]Butanoic Acid
CAS No.	99633-82-6
Molecular Formula	C₁₄H₂₀N₂O₅
Molecular Weight	296.32 g/mol
Synonyms	L-2-Amino-4-[[2-hydroxy-2-(4-hydroxyphenyl)ethyl]carbamoyl]butanoic acid; (S)-2-Amino-4-((2-hydroxy-2-(4-hydroxyphenyl)ethyl)carbamoyl)butanoic acid; N-[2-Hydroxy-2-(4-hydroxyphenyl)ethyl]-L-glutamine; Tyrosine-glutamine derivative; 99633-82-6; L-Glutamine, N-[2-hydroxy-2-(4-hydroxyphenyl)ethyl]-; A specialized tyrosine-glutamine hybrid amino acid
EINECS	Contact for details

Quality Control

Our (2S)-2-Amino-4-[[2-Hydroxy-2-(4-Hydroxyphenyl)Ethyl]Carbamoyl]Butanoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification and impurity profiling, to ensure it meets the high standards required for research and pharmaceutical development. Certificates of Analysis (COA) with detailed chromatographic data (HPLC, LC-MS) are provided to guarantee traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions when necessary to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.