Description

n-2-Naphthalenyl-L-Leucine is a specialized non-proteinogenic amino acid derivative featuring a naphthalene moiety linked to the L-leucine backbone. This compound is valued for its role as a key chiral building block and intermediate in advanced organic synthesis, particularly in the development of pharmaceuticals and bioactive molecules. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries who require high-purity, structurally complex intermediates for drug discovery and process development.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral synthon in the research and synthesis of novel active pharmaceutical ingredients (APIs), especially for compounds targeting neurological or metabolic pathways.
• Peptidomimetics Research: Used in the design and construction of peptidomimetics and constrained peptides, where the bulky naphthyl group can influence conformation and receptor binding.
• Agrochemical Synthesis: Acts as a building block for developing new crop protection agents and herbicides with enhanced specificity.
• Biochemical Tool Compound: Employed in academic and industrial research as a probe to study enzyme-substrate interactions or as a standard in analytical method development.
• Fine Chemical Production: Utilized in the multi-step synthesis of complex organic molecules for material science and specialty chemical applications.

Basic Information

Product Name	n-2-Naphthalenyl-L-Leucine
CAS No.	99631-79-5
Molecular Formula	C₁₆H₁₉NO₂
Molecular Weight	257.33 g/mol
Synonyms	L-Leucine, N-(2-naphthalenyl)-; (S)-2-Amino-4-methyl-N-(naphthalen-2-yl)pentanamide; N-(2-Naphthyl)-L-leucine; 2-Naphthyl-L-leucine; N-2-Naphthylleucine; 99631-79-5; N-(Naphthalen-2-yl)-L-leucine
EINECS	Contact for details

Quality Control

Our n-2-Naphthalenyl-L-Leucine is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.