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(R)-2,2'-Binaphthyl-17-Crown-5 CAS NO 99630-51-0


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CAS No.:99630-51-0

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

(R)-2,2'-Binaphthyl-17-Crown-5 is a chiral crown ether derivative, specifically an (R)-enantiomer, featuring a binaphthyl backbone integrated into a 17-crown-5 ether structure. This compound is highly valued for its ability to selectively bind and transport specific cations, making it a critical component in advanced chemical synthesis and analytical separations. It is primarily utilized by researchers and manufacturers in the pharmaceutical, fine chemical, and materials science industries for applications such as asymmetric synthesis, chiral recognition, and sensor development.

Application

  • Chiral Phase-Transfer Catalyst: Employed in asymmetric synthesis to induce enantioselectivity in alkylation and other key reactions.
  • Chiral Selector for Chromatography: Used as a stationary phase modifier or additive in HPLC and capillary electrophoresis for the separation of enantiomers.
  • Ion-Selective Electrodes & Sensors: Serves as an ionophore in membrane electrodes for the potentiometric detection of specific alkali and alkaline earth metal ions.
  • Molecular Recognition Studies: Acts as a host molecule in supramolecular chemistry for studying guest-host interactions and designing molecular devices.
  • Asymmetric Membrane Transport: Facilitates the enantioselective transport of ions across liquid membranes, relevant for separation technologies.
  • Optical Resolution Agent: Used for the direct resolution of racemic mixtures of chiral ammonium salts and other cationic compounds.

Basic Information

Product Name (R)-2,2'-Binaphthyl-17-Crown-5
CAS No. 99630-51-0
Molecular Formula C₃₀H₂₈O₅
Molecular Weight 468.54 g/mol
Synonyms (R)-(-)-2,2'-Binaphthyl-17-crown-5; (R)-1,1'-Binaphthalene-2,2'-diyl 17-crown-5; (R)-BNC-17-C-5; (R)-Binaphtho-17-crown-5; (R)-2,2'-Bis[1,4,7,10,13-pentaoxacyclopentadec-2-yloxy]-1,1'-binaphthyl; (R)-Enantiomer of 2,2'-Binaphthyl-17-Crown-5 Ether; (R)-1,1'-Binaphthyl-2,2'-diyl pentaglycol ether
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Quality Control

Our (R)-2,2'-Binaphthyl-17-Crown-5 is produced under strict quality management protocols to ensure high chiral purity and chemical integrity. Each batch is characterized by advanced analytical techniques, including chiral HPLC, to confirm enantiomeric excess (ee) and overall purity. Certificates of Analysis (COA) detailing specific results for identity, assay, and chiral purity are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture absorption, which could affect performance. Handle and store under an inert atmosphere for long-term stability.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 98.0%
Chiral Purity (Enantiomeric Excess) ≥ 99.0% ee
Loss on Drying ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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