Description

5-Ethynyl-2-Methyl-Phenol is a high-purity phenolic compound featuring an ethynyl functional group, making it a versatile and valuable building block in advanced organic synthesis. Its unique structure is critical for constructing complex molecular architectures, particularly in pharmaceutical and agrochemical research and development. This intermediate is essential for chemists and manufacturers in the fine chemical, life science, and material science industries seeking to develop novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and production of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the development of next-generation pesticides, herbicides, and plant growth regulators due to its reactive phenolic and alkyne moieties.
• Material Science Precursor: Serves as a monomer or cross-linking agent in the synthesis of specialized polymers, resins, and advanced organic frameworks with tailored properties.
• Ligand and Catalyst Development: Employed in the design and synthesis of novel ligands for metal-organic catalysis and coordination chemistry applications.
• Chemical Research & Development: A fundamental building block in academic and industrial R&D for exploring new organic reactions and synthesizing complex heterocyclic compounds.
• Fine Chemical Manufacturing: Integral to the multi-step synthesis of high-value, low-volume specialty chemicals for various industrial applications.

Basic Information

Product Name	5-Ethynyl-2-Methyl-Phenol
CAS No.	99595-47-8
Molecular Formula	C9H8O
Molecular Weight	132.16 g/mol
Synonyms	2-Methyl-5-ethynylphenol; 5-Ethynyl-o-cresol; 2-Hydroxy-4-methylphenylacetylene; 4-Methyl-2-(ethynyl)phenol; 2-Methyl-5-(ethynyl)phenol; 5-Ethynyl-2-methylphenol; Phenol, 5-ethynyl-2-methyl-; 99595-47-8
EINECS	Contact for details

Quality Control

Our 5-Ethynyl-2-Methyl-Phenol is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to confirm identity, potency, and impurity profiles. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, open flames, and incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.