Description

(+/-)-3-Aminohexahydro-2H-Azepin-2-One Hydrochloride CAS NO 99560-25-5 is a high-purity chiral building block and pharmaceutical intermediate. This compound is valued for its azepane scaffold, which is a privileged structure in medicinal chemistry for modulating biological activity. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents, particularly in areas requiring advanced heterocyclic chemistry.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates.
• Medicinal Chemistry Research: Used as a versatile scaffold for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Protease Inhibitor Development: The azepinone core is relevant in the design of inhibitors for various proteolytic enzymes.
• Chemical Biology Probes: Employed in the synthesis of molecular probes to study biological pathways and target engagement.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring functionalized azepane derivatives.
• Academic Research: Used in universities and research institutes for methodological development in organic synthesis and asymmetric catalysis.

Basic Information

Product Name	(+/-)-3-Aminohexahydro-2H-Azepin-2-One Hydrochloride
CAS No.	99560-25-5
Molecular Formula	C6H13N3O • HCl
Molecular Weight	179.65 g/mol
Synonyms	3-Aminoazepan-2-one hydrochloride; (±)-3-Aminohexahydro-2H-azepin-2-one hydrochloride; rac-3-Amino-2-azepanone hydrochloride; 2-Azepinone, 3-aminohexahydro-, hydrochloride, (±)-; 3-Amino-2-azepanone hydrochloride; DL-3-Aminohexahydro-2H-azepin-2-one HCl; Azepan-2-one, 3-amino-, hydrochloride
EINECS	Contact for details

Quality Control

Our (+/-)-3-Aminohexahydro-2H-Azepin-2-One Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by spectroscopic methods, to ensure it meets exacting standards for research and development use. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. Keep container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.