Description

Boc-Lys-OMe.HCl is a protected amino acid derivative, specifically the methyl ester hydrochloride salt of Nα-Boc-L-lysine. This compound is a crucial building block in solid-phase peptide synthesis (SPPS), valued for its role in introducing lysine residues while protecting the side-chain amine. It is primarily needed by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in the production of therapeutic peptides, biochemical probes, and complex organic molecules.

Application

• Peptide Synthesis: A fundamental reagent for the controlled incorporation of lysine into peptide chains during Fmoc/t-Boc solid-phase or solution-phase synthesis.
• Pharmaceutical Intermediates: Serves as a key intermediate in the research and development of peptide-based drugs, including hormones, antibiotics, and enzyme inhibitors.
• Bioconjugation & Labeling: Used to introduce reactive amine handles (after deprotection) for attaching fluorescent dyes, biotin, or other functional groups to biomolecules.
• Chemical Biology Research: Employed in the synthesis of custom peptides for studying protein-protein interactions, enzyme kinetics, and cellular signaling pathways.
• Material Science: Acts as a monomer or precursor for creating peptide-modified surfaces, hydrogels, and other bio-inspired polymeric materials.

Basic Information

Product Name	Boc-Lys-OMe.HCl
CAS No.	99532-86-2
Molecular Formula	C12H25ClN2O4
Molecular Weight	296.79 g/mol
Synonyms	Nα-Boc-L-lysine methyl ester hydrochloride; Boc-L-Lys-OMe · HCl; Methyl N2-[(tert-butoxy)carbonyl]-L-lysinate hydrochloride; (S)-Methyl 2-((tert-butoxycarbonyl)amino)-6-aminohexanoate hydrochloride; Boc-Lys-OMe hydrochloride; tert-Butyloxycarbonyl-L-lysine methyl ester hydrochloride; N-Boc-L-lysine methyl ester HCl
EINECS	Contact for details

Quality Control

Our Boc-Lys-OMe.HCl is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and identity confirmation. Certificates of Analysis (COA) detailing specific results for assay, optical rotation, and related substances are provided to ensure compliance with research and pharmaceutical intermediate standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. The product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Optical Rotation [α]D20	+15.0° to +18.0° (c=1 in methanol)
Chiral Purity (HPLC)	≥99.0%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.