Description

4-Desmethoxypropoxyl-4-Methylthio Rabeprazole is a key pharmaceutical intermediate in the synthesis of advanced proton pump inhibitors. This compound matters for its role in developing next-generation gastrointestinal therapeutics with potentially improved pharmacokinetic profiles. It is primarily needed by pharmaceutical R&D laboratories, API (Active Pharmaceutical Ingredient) manufacturers, and fine chemical suppliers serving the global healthcare sector.

Application

• Pharmaceutical Intermediate: Critical building block in the synthesis of novel Rabeprazole analogs and related benzimidazole derivatives.
• Active Pharmaceutical Ingredient (API) Research: Used in preclinical and clinical development of new acid-suppression medications.
• Process Chemistry & Scale-Up: Serves as a reference standard and starting material for process optimization and impurity profiling in API manufacturing.
• Academic & Contract Research: Utilized in university and CRO settings for pharmacological studies and structure-activity relationship (SAR) exploration.
• Analytical Standard: Employed as a high-purity certified reference material (CRM) for quality control and regulatory testing.

Basic Information

Product Name	4-Desmethoxypropoxyl-4-Methylthio Rabeprazole
CAS No.	99487-86-2
Molecular Formula	C17H19N3O2S2
Molecular Weight	361.48 g/mol
Synonyms	4-Desmethoxypropoxyl-4-Methylthio Rabeprazole; Rabeprazole Impurity; Rabeprazole Related Compound; 2-[[[4-(3-Methoxypropoxy)-3-methyl-2-pyridinyl]methyl]sulfinyl]-1H-benzimidazole derivative; 4-Methylthio-4-desmethoxypropoxy Rabeprazole; Desmethoxypropoxyl Methylthio Rabeprazole; CAS 99487-86-2
EINECS	Contact for details

Quality Control

Our 4-Desmethoxypropoxyl-4-Methylthio Rabeprazole is manufactured under strict quality management systems. We provide material that meets exacting standards for pharmaceutical intermediate applications, with comprehensive impurity profiling and identity confirmation. Certificates of Analysis (COA) detailing purity, related substances, and analytical methods (HPLC, NMR) are available upon request to support your regulatory and R&D needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to protect the material from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.