Description

2R-1-Aza-Bicyclo[2.2.1]Hept-2-Ylamine is a high-purity, chiral bicyclic amine building block of significant interest in advanced organic synthesis. This compound matters as a versatile precursor for constructing complex nitrogen-containing heterocycles, which are core scaffolds in modern pharmaceuticals and agrochemicals. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries for developing new active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and antiviral research.
• Ligand and Catalyst Development: Used to create novel chiral ligands for asymmetric catalysis, enhancing the enantioselectivity of chemical transformations.
• Agrochemical Synthesis: Serves as a building block for developing new, more selective herbicides, fungicides, and insecticides.
• Academic and Industrial R&D: Employed in methodological studies and the discovery of new chemical reactions and processes.
• Fine Chemical Production: Integral in the multi-step synthesis of complex, high-value specialty chemicals and flavors/fragrances.

Basic Information

Product Name	2R-1-Aza-Bicyclo[2.2.1]Hept-2-Ylamine
CAS No.	99445-19-9
Molecular Formula	C6H12N2
Molecular Weight	112.17 g/mol
Synonyms	(2R)-1-Azabicyclo[2.2.1]heptan-2-amine; (2R)-2-Amino-1-azabicyclo[2.2.1]heptane; (2R)-1-Azabicyclo[2.2.1]hept-2-ylamine; (2R)-2-Aminoquinuclidine; endo-(2R)-2-Amino-1-azabicyclo[2.2.1]heptane; (R)-1-Azabicyclo[2.2.1]heptan-2-amine; (R)-2-Aminoquinuclidine; 2R-Azabicycloheptylamine
EINECS	Contact for details

Quality Control

Our 2R-1-Aza-Bicyclo[2.2.1]Hept-2-Ylamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with exacting R&D and process chemistry standards. Certificates of Analysis (COA) with full analytical data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect purity and stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.