Description

4-Desacetyl 3-Deoxy Vincristine is a key synthetic intermediate in the production of complex pharmaceutical compounds. This compound matters for its critical role in the research and development of novel chemotherapeutic agents and other bioactive molecules. It is primarily needed by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic research institutions focused on oncology drug discovery and advanced organic synthesis.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of advanced Vinca alkaloid derivatives and related anticancer agents.
• Oncology Research: Used in the development and study of new chemotherapeutic compounds targeting various cancer cell lines.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method validation in pharmaceutical manufacturing.
• Process Chemistry: Employed in scale-up and optimization studies for the production of complex active pharmaceutical ingredients (APIs).
• Biochemical Research: Utilized in studies investigating tubulin binding and the mechanism of action of microtubule-targeting drugs.
• Academic Synthesis: A valuable compound for teaching and research in advanced organic and medicinal chemistry.

Basic Information

Product Name	4-Desacetyl 3-Deoxy Vincristine
CAS No.	99435-53-7
Molecular Formula	C44H54N4O9
Molecular Weight	782.93 g/mol
Synonyms	3'-Deoxy-4'-desacetylvincristine; 4'-Desacetyl-3'-deoxyvincristine; 3'-Deoxy-4'-desacetyl-VCR; 4-Desacetyl-3-deoxyvincristine; Desacetyl Deoxyvincristine; Vincristine Impurity; 99435-53-7; 4-Desacetyl-3-deoxy-Vincristine
EINECS	Contact for details

Quality Control

Our 4-Desacetyl 3-Deoxy Vincristine is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements for pharmaceutical research and development. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.