Description

2-Oxabicyclo[3.1.0]Hexane-6-Carboxylic Acid is a specialized bicyclic organic compound featuring a fused oxirane and cyclopentane ring system, serving as a versatile chiral building block in advanced organic synthesis. Its constrained three-dimensional structure and carboxylic acid functionality make it a valuable intermediate for constructing complex molecules with precise stereochemistry. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and the synthesis of active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in antiviral, anticancer, and central nervous system (CNS) drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where its unique scaffold can contribute to biological activity and selectivity.
• Asymmetric Catalysis Ligand Precursor: Serves as a starting material for the synthesis of novel chiral ligands and organocatalysts used in enantioselective transformations.
• Material Science Research: Investigated as a monomer or cross-linking agent for creating polymers with specific thermal or mechanical properties derived from its strained ring system.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes to study enzyme mechanisms or protein-ligand interactions due to its potential as a reactive warhead or stereochemical tag.

Basic Information

Product Name	2-Oxabicyclo[3.1.0]Hexane-6-Carboxylic Acid
CAS No.	99418-15-2
Molecular Formula	C7H8O3
Molecular Weight	140.14 g/mol
Synonyms	6-Carboxy-2-oxabicyclo[3.1.0]hexane; (1R,5S)-6-Oxabicyclo[3.1.0]hexane-3-carboxylic Acid (for specific enantiomer); Bicyclo[3.1.0]hexane-6-carboxylic acid, 2-oxa-; Oxabicyclohexanecarboxylic Acid; CAS 99418-15-2
EINECS	Contact for details

Quality Control

Every batch of 2-Oxabicyclo[3.1.0]Hexane-6-Carboxylic Acid is manufactured under strict quality management systems. We provide comprehensive analytical documentation, including a Certificate of Analysis (COA) detailing purity, enantiomeric excess (where applicable), and impurity profiles. Our quality protocols are designed to meet the stringent requirements of cGMP and ISO standards for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.