Description

trans-1,2-Cyclopentanediamine Hydrochloride is a high-purity chiral diamine salt, serving as a critical building block in asymmetric synthesis and pharmaceutical development. Its rigid cyclopentane backbone and defined stereochemistry make it an invaluable ligand and precursor for creating complex, optically active molecules. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require reliable, high-quality chiral intermediates.

Application

• Pharmaceutical Intermediate: Key chiral building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in antiviral and central nervous system (CNS) drug candidates.
• Asymmetric Catalyst Ligand: Used to construct chiral ligands for transition metal catalysis, enabling enantioselective hydrogenation, cyclization, and cross-coupling reactions.
• Agrochemical Synthesis: Intermediate in the production of chiral herbicides, fungicides, and plant growth regulators requiring specific stereochemistry for efficacy.
• Resolution Agent: Employed as a chiral resolving agent for the separation of racemic mixtures of carboxylic acids and other compounds.
• Polymer Modification: Serves as a monomer or cross-linking agent for producing specialty polyamides and polyurethanes with enhanced thermal or mechanical properties.
• Chemical Research & Development: A versatile scaffold in medicinal chemistry and organic synthesis for exploring new chemical entities and reaction pathways.

Basic Information

Product Name	trans-1,2-Cyclopentanediamine Hydrochloride
CAS No.	99363-25-4
Molecular Formula	C5H12N2·HCl
Molecular Weight	152.63 g/mol
Synonyms	(1R,2R)-1,2-Cyclopentanediamine Hydrochloride; (1R,2R)-1,2-Diaminocyclopentane Hydrochloride; trans-(1R,2R)-1,2-Cyclopentanediamine Monohydrochloride; (1R,2R)-Cyclopentane-1,2-diamine Hydrochloride; trans-1,2-Diaminocyclopentane HCl; (R,R)-1,2-Cyclopentanediamine HCl; (1R,2R)-1,2-Cyclopentylenediamine Hydrochloride
EINECS	Contact for details

Quality Control

Our trans-1,2-Cyclopentanediamine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets stringent specifications for identity, purity, and chiral integrity. Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data are provided to guarantee traceability and batch-to-batch consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee (trans-(1R,2R) isomer)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.