Description

Methyl (2S)-2-Amino-3-(4-Bromophenyl)Propanoate is a chiral, non-natural amino acid ester derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its role as a versatile intermediate for constructing complex molecules with high stereochemical purity. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for the synthesis of active pharmaceutical ingredients (APIs), peptide mimetics, and specialized fine chemicals.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and production of novel therapeutic agents, including enzyme inhibitors and receptor modulators.
• Peptidomimetics & Bioactive Molecule Synthesis: Used to incorporate the 4-bromophenylalanine moiety into peptide backbones to enhance metabolic stability and binding affinity.
• Agrochemical Research: Serves as a precursor in developing new crop protection agents and herbicides with specific chiral activity.
• Chemical Biology & Proteomics: Employed as a building block for activity-based probes and labeled compounds to study biological pathways.
• Asymmetric Catalysis & Method Development: A valuable substrate for testing new catalytic systems and synthetic methodologies in academic and industrial R&D.
• Custom Synthesis & Contract Manufacturing: A high-purity starting material for custom synthesis projects requiring specific enantiomeric purity.

Basic Information

Product Name	Methyl (2S)-2-Amino-3-(4-Bromophenyl)Propanoate
CAS No.	99359-33-8
Molecular Formula	C10H12BrNO2
Molecular Weight	258.11 g/mol
Synonyms	(S)-Methyl 2-amino-3-(4-bromophenyl)propanoate; L-4-Bromophenylalanine methyl ester; Methyl L-4-bromophenylalaninate; (2S)-2-Amino-3-(4-bromophenyl)propanoic acid methyl ester; Methyl (S)-2-amino-3-(p-bromophenyl)propionate; p-Bromo-L-phenylalanine methyl ester; (S)-Methyl 4-bromophenylalaninate; Methyl (S)-4-bromophenylalaninate
EINECS	Contact for details

Quality Control

Our Methyl (2S)-2-Amino-3-(4-Bromophenyl)Propanoate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and enantiomeric excess.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.