Description

(3S,4'R)-3Aβ,4,5,6,6Aβ,7,8,9,9Aβ,9Bα-Decahydro-4β-Hydroxy-4'-Methyl-6,9-Bismethylenespiro[Azuleno[4,5-B]Furan-3(2H),2'-Oxetan]-2-One is a complex, high-purity spirocyclic organic compound with a defined stereochemistry. This compound is of significant value as a key chiral intermediate or building block in advanced organic synthesis, particularly for the development of novel active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily sought after by pharmaceutical R&D laboratories and specialty chemical manufacturers engaged in the synthesis of complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral building block in the multi-step synthesis of novel drug candidates, especially in oncology and antiviral research.
• Advanced Organic Synthesis: Used in the construction of complex spirocyclic and polycyclic frameworks for academic and industrial research.
• Asymmetric Catalysis Research: Employed as a substrate or ligand precursor in the development of new stereoselective catalytic reactions.
• Fine Chemical Production: Acts as a starting material for the manufacture of high-value, low-volume specialty chemicals with specific biological or material properties.
• Reference Standard: Utilized as an analytical standard in method development and quality control for related pharmaceutical processes.

Basic Information

Item	Details
Product Name	(3S,4'R)-3Aβ,4,5,6,6Aβ,7,8,9,9Aβ,9Bα-Decahydro-4β-Hydroxy-4'-Methyl-6,9-Bismethylenespiro[Azuleno[4,5-B]Furan-3(2H),2'-Oxetan]-2-One
CAS No.	99305-07-4
Molecular Formula	C19H24O4
Molecular Weight	316.39 g/mol
Synonyms	Spiro[azuleno[4,5-b]furan-3(2H),2'-oxetan]-2-one, decahydro-4-hydroxy-4'-methyl-6,9-bis-methylene-, (3S,3aβ,4β,6aβ,9aβ,9bα,4'R)-; 99305-07-4; (3S,4'R)-Decahydro-4-hydroxy-4'-methyl-6,9-bis-methylenespiro[azuleno[4,5-b]furan-3(2H),2'-oxetan]-2-one; Azuleno-fused spirooxetane derivative; Complex spirocyclic lactone intermediate.
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems. Every batch is characterized and tested using advanced analytical techniques including HPLC, GC, NMR, and MS to ensure identity, purity, and stereochemical integrity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment. We support cGMP compliance for pharmaceutical applications and can tailor purity grades to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The container should be kept in a well-ventilated area and protected from moisture. For long-term storage, consider inert gas purging.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.