Description

Hydroxy Torsemide CAS NO 99300-68-2 is a key pharmaceutical intermediate and reference standard, primarily used in the research and development of diuretic medications. This compound is critical for ensuring the quality, efficacy, and safety of active pharmaceutical ingredients (APIs) in the final drug formulation. It is an essential material for pharmaceutical manufacturers, analytical laboratories, and research institutions focused on cardiovascular and renal therapeutics.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of Torsemide and related diuretic APIs.
• Reference Standard: Used for quality control, method validation, and calibration in analytical testing (HPLC, GC-MS).
• Metabolite Studies: Employed in pharmacokinetic and metabolic pathway research for diuretic drugs.
• Impurity Profiling: Serves as a known impurity or degradation product standard to ensure API purity.
• Clinical Research: Utilized in preclinical and clinical studies to understand drug action and metabolism.
• Regulatory Submissions: Provides certified material for documentation required by agencies like the FDA and EMA.

Basic Information

Product Name	Hydroxy Torsemide
CAS No.	99300-68-2
Molecular Formula	C₁₆H₂₀N₄O₄S
Molecular Weight	364.42 g/mol
Synonyms	1-Isopropyl-3-[(4-m-toluidino-3-pyridyl)sulfonyl]urea; 3-[(4-(3-Methylphenyl)amino-3-pyridinyl)sulfonyl]-1-(1-methylethyl)urea; Hydroxytorsemide; Torsemide Impurity; Torsemide Metabolite; Torsemide Related Compound; UNII-8WZ8M8361C
EINECS	Contact for details

Quality Control

Our Hydroxy Torsemide is manufactured under strict quality management systems. Each batch is tested to ensure it meets high-purity standards suitable for pharmaceutical research and development. Comprehensive testing includes identification, assay, and impurity profile analysis via validated methods such as HPLC and spectroscopy. A Certificate of Analysis (COA) is provided with every shipment, detailing all quality parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.