Description

n-Formylboromycin is a structurally complex boron-containing macrolide derivative with demonstrated biological activity in antimicrobial and antifungal research. It serves as a high-value reference standard and synthetic intermediate for pharmaceutical R&D, particularly in the development of boron-based therapeutics. Researchers in academic laboratories, contract research organizations (CROs), and biopharmaceutical companies rely on its well-characterized purity and stability for mechanistic studies and structure–activity relationship (SAR) profiling. n-Formylboromycin CAS NO 99292-91-8 is supplied under stringent quality controls to ensure batch-to-batch reproducibility and analytical reliability.

Application

• Pharmaceutical reference standard for HPLC and LC-MS method validation
• Synthetic building block in the development of boron-enriched antibiotics and antifungal agents
• Biochemical probe for studying boron-dependent enzyme inhibition mechanisms
• Lead compound optimization in medicinal chemistry campaigns targeting resistant pathogens
• Quality control material for boromycin-class natural product assays
• Calibration standard in quantitative microbial susceptibility testing (MIC determination)
• Stability-indicating assay component for forced degradation studies
• Research tool in boron neutron capture therapy (BNCT) precursor investigations

Basic Information

Product Name	n-Formylboromycin
CAS No.	99292-91-8
Molecular Formula	C37H62BNO10
Molecular Weight	691.72 g/mol
Synonyms	Formylboromycin; Boromycin formyl derivative; n-Formyl-boromycin; NSC 632547; BRN 4962972; 99292-91-8; Boromycin, N-formyl-; Formylated boromycin; Boromycin N-formyl analog
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request. Each batch is verified for identity (IR, HPLC retention time), purity (≥98.5% by HPLC), and absence of critical impurities (heavy metals, residual solvents). Testing follows ACS Reagent Grade and EP/USP general chapters where applicable, supporting regulatory submissions and GLP-compliant research.

Storage

Preserve in a tightly closed container, protected from light. Store at 2–8 °C under inert atmosphere (argon or nitrogen) to prevent degradation. Due to its hygroscopic nature, maintain low-humidity conditions (<30% RH) and minimize exposure to ambient air during handling.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches certified reference standard
Assay (HPLC)	98.5% – 101.0%
Related Substances (HPLC)	≤1.5% total impurities
Residual Solvents (GC)	Meets ICH Q3C limits
Water Content (KF)	≤0.5%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.