Description

4-Amino-5-Hydroxy-2-Oxo-7-Oxabicyclo[4.1.0]Hept-3-Ene-3-Carboxamide is a high-value, specialized bicyclic compound with a complex oxabicycloheptene core structure. This molecule is a critical advanced intermediate in the synthesis of novel pharmaceutical agents, particularly in the development of antibiotics and other bioactive molecules. It is primarily sought by research institutions, fine chemical manufacturers, and pharmaceutical companies engaged in cutting-edge drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel β-lactam antibiotics and other complex therapeutic agents.
• Antibiotic Research: Serves as a core scaffold in the development of new classes of antibacterial compounds targeting resistant pathogens.
• Medicinal Chemistry: Used in structure-activity relationship (SAR) studies and lead optimization for drug discovery programs.
• Fine Chemical Synthesis: Employed in multi-step organic syntheses to construct complex molecular architectures with biological activity.
• Biochemical Research: Utilized as a probe or precursor in studying enzyme inhibition and biological pathways.

Basic Information

Product Name	4-Amino-5-Hydroxy-2-Oxo-7-Oxabicyclo[4.1.0]Hept-3-Ene-3-Carboxamide
CAS No.	99291-28-8
Molecular Formula	C7H8N2O5
Molecular Weight	200.15 g/mol
Synonyms	7-Oxa-1-azabicyclo[4.1.0]hept-3-ene-3-carboxamide, 4-amino-5-hydroxy-2-oxo-; (1S,5R,6S)-4-Amino-5-hydroxy-2-oxo-7-oxabicyclo[4.1.0]hept-3-ene-3-carboxamide; 4-Amino-5-hydroxy-2-oxo-7-oxa-1-azabicyclo[4.1.0]hept-3-ene-3-carboxylic acid amide; Carbapenem intermediate; Oxabicycloheptene carboxamide derivative
EINECS	Contact for details

Quality Control

Our production of 4-Amino-5-Hydroxy-2-Oxo-7-Oxabicyclo[4.1.0]Hept-3-Ene-3-Carboxamide adheres to stringent quality protocols suitable for pharmaceutical intermediate applications. Every batch is characterized and tested to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing specifications such as assay (HPLC), chiral purity, and impurity profiles are provided with each shipment. Our quality system supports compliance with cGMP and ICH guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under a dry atmosphere to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.