Description

Bisanhydro-13-Dihydrodaunomycinone is a key anthracycline derivative and an important intermediate in the synthesis of complex pharmaceutical compounds. This high-purity intermediate is critical for research and development in the production of novel chemotherapeutic agents and other bioactive molecules. It is primarily utilized by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions focused on oncology drug discovery and advanced organic synthesis.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of anthracycline-based anticancer drugs and their analogs.
• Research & Development: Used in medicinal chemistry programs for the development of new chemotherapeutic agents targeting DNA topoisomerase II.
• Reference Standard: Employed as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Biochemical Research: Utilized in studies investigating the structure-activity relationships (SAR) of anthracycline antibiotics.
• Fine Chemical Synthesis: Acts as a specialized intermediate for the custom synthesis of complex organic molecules in contract manufacturing.

Basic Information

Product Name	Bisanhydro-13-Dihydrodaunomycinone
CAS No.	99260-72-7
Molecular Formula	C21H16O7
Molecular Weight	380.35 g/mol
Synonyms	13,13'-Bisanhydro-13-dihydrodaunomycinone; 4,11-Dihydroxy-12-[(2R,4S,5S,6S)-4-hydroxy-6-methyl-5-oxooxan-2-yl]-6,10-dioxo-7H-tetracene-2-carbaldehyde; Daunomycinone, bisanhydro-13-dihydro-; Anthracycline intermediate; 7-Deoxy-13-dihydrodaunomycinone bisanhydro derivative
EINECS	Contact for details

Quality Control

Our Bisanhydro-13-Dihydrodaunomycinone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, IR and NMR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or cGMP-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Yellow to orange powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.