Description

4-Amino-5-Chloro-2-Methoxy-n-[2-[(4-Methoxybenzyl)Methylamino]-1,1-Dimethylethyl]Benzamide is a high-purity, synthetically derived benzamide derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical pharmaceutical intermediate for the synthesis of complex active pharmaceutical ingredients (APIs), particularly those targeting neurological and gastrointestinal pathways. It is primarily utilized by pharmaceutical manufacturers and contract research organizations (CROs) engaged in the development of novel therapeutics.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug molecules, particularly for neurological and gastrointestinal indications.
• Active Pharmaceutical Ingredient (API) Synthesis: Used in multi-step synthetic routes for the production of proprietary APIs.
• Biochemical Research: Employed as a reference standard or reagent in pharmacological and receptor-binding studies.
• Process Development & Scale-Up: Serves as a critical material for optimizing synthetic routes from laboratory to commercial production scale.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	4-Amino-5-Chloro-2-Methoxy-n-[2-[(4-Methoxybenzyl)Methylamino]-1,1-Dimethylethyl]Benzamide
CAS No.	99260-61-4
Molecular Formula	C23H32ClN3O3
Molecular Weight	433.97 g/mol
Synonyms	4-Amino-5-chloro-2-methoxy-N-[2-[(4-methoxybenzyl)methylamino]-1,1-dimethylethyl]benzamide; 4-Amino-5-chloro-2-methoxy-N-[2-[(4-methoxyphenyl)methyl]methylamino]-1,1-dimethylethyl]benzamide; 4-Amino-5-chloro-2-methoxy-N-[2-(N-methyl-4-methoxybenzylamino)-1,1-dimethylethyl]benzamide; Benzamide, 4-amino-5-chloro-2-methoxy-N-[2-[(4-methoxybenzyl)methylamino]-1,1-dimethylethyl]-; Itopride Intermediate; Itopride Hydrochloride Intermediate; CAS 99260-61-4
EINECS	Contact for details

Quality Control

Our 4-Amino-5-Chloro-2-Methoxy-n-[2-[(4-Methoxybenzyl)Methylamino]-1,1-Dimethylethyl]Benzamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and identity. Certificates of Analysis (COA) detailing purity, impurities, and physical characteristics are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Single Maximum Impurity (HPLC)	≤ 1.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.