Description

trans-2-(2-Methoxyphenyl)-5-Oxotetrahydrofuran-3-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its specific stereochemistry and functional groups. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs) and fine chemicals, where precise molecular architecture is required. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new therapeutic agents and specialty products.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-inflammatory research.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides with specific activity profiles.
• Organic Synthesis Research: Serves as a versatile chiral synthon for constructing complex heterocyclic compounds in academic and industrial R&D.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals requiring the tetrahydrofuran carboxylic acid scaffold.
• Process Chemistry Development: Used for scaling up synthetic routes and optimizing manufacturing processes for target molecules.

Basic Information

Product Name	trans-2-(2-Methoxyphenyl)-5-Oxotetrahydrofuran-3-Carboxylic Acid
CAS No.	99226-02-5
Molecular Formula	C13H14O5
Molecular Weight	250.25 g/mol
Synonyms	trans-2-(2-Methoxyphenyl)-5-oxotetrahydrofuran-3-carboxylic acid; 3-Carboxy-2-(2-methoxyphenyl)dihydro-2(3H)-furanone; 2-(2-Methoxyphenyl)-5-oxotetrahydro-3-furancarboxylic acid; (3R,4R)-2-(2-Methoxyphenyl)-5-oxotetrahydrofuran-3-carboxylic acid (stereoisomer); 99226-02-5; Tetrahydrofuran-3-carboxylic acid, 2-(2-methoxyphenyl)-5-oxo-; Dihydro-2(3H)-furanone, 3-carboxy-2-(2-methoxyphenyl)-
EINECS	Contact for details

Quality Control

Our trans-2-(2-Methoxyphenyl)-5-Oxotetrahydrofuran-3-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral analysis, to ensure it meets the high standards required for pharmaceutical R&D and production. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.