Description

(S)-3,3-Dimethyltetrahydropyrrolo[1,2-C]Oxazol-5(3H)-One is a high-value, chiral oxazolone derivative that serves as a critical synthetic intermediate in advanced organic synthesis. Its importance lies in its role as a key building block for constructing complex molecules with defined stereochemistry, enabling the production of high-purity active pharmaceutical ingredients (APIs). This compound is essential for research and development chemists and process engineers in the pharmaceutical, agrochemical, and specialty chemical industries who require reliable, high-quality chiral synthons.

Application

• Pharmaceutical Intermediate: A key chiral building block in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and antiviral therapies.
• Asymmetric Synthesis: Used as a precursor or auxiliary in catalytic asymmetric reactions to introduce stereogenic centers with high enantiomeric excess.
• Agrochemical Development: Employed in the research and production of enantiomerically pure pesticides and herbicides for enhanced efficacy.
• Process Chemistry: Serves as a starting material or intermediate in scalable process development for commercial API manufacturing.
• Academic & Contract Research: Utilized in medicinal chemistry programs and custom synthesis projects within research organizations (CROs).
• Peptidomimetics & Bioactive Molecule Synthesis: Acts as a constrained scaffold for designing and synthesizing peptide analogs and other bioactive compounds.

Basic Information

Product Name	(S)-3,3-Dimethyltetrahydropyrrolo[1,2-C]Oxazol-5(3H)-One
CAS No.	99208-71-6
Molecular Formula	C9H15NO2
Molecular Weight	169.22 g/mol
Synonyms	(S)-3,3-Dimethyltetrahydropyrrolo[1,2-c][1,3]oxazol-5(3H)-one; (S)-3,3-Dimethyl-1,3,3a,4,6,6a-hexahydropyrrolo[3,4-c]isoxazol-5-one; (S)-3,3-Dimethyltetrahydropyrrolooxazolone; (S)-DMPO; (S)-Hexahydropyrrolo[3,4-c]isoxazol-5-one, 3,3-dimethyl-; Chiral Oxazolone Derivative; (S)-Enantiomer of 3,3-Dimethyltetrahydropyrrolooxazol-5-one
EINECS	Contact for details

Quality Control

Our (S)-3,3-Dimethyltetrahydropyrrolo[1,2-C]Oxazol-5(3H)-One is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral HPLC for enantiomeric purity and standard pharmacopeial identification tests, to ensure it meets the high standards required for pharmaceutical R&D and production. Certificates of Analysis (COA) with detailed chromatographic data are provided for full traceability and quality assurance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and performance. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.