Description

(+-)-(R*,S*)-6-Fluoro-3,4-Dihydro-α-[[(Phenylmethyl)Amino]Methyl]-2H-1-Benzopyran-2-Methanol is a high-purity chiral benzopyran derivative, serving as a critical advanced pharmaceutical intermediate. Its value lies in its complex molecular architecture, which provides a versatile scaffold for the synthesis of novel therapeutic agents targeting the central nervous system. This compound is essential for research and development chemists in the pharmaceutical industry, particularly those focused on developing new neuroactive drugs, receptor modulators, and other bioactive molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs), especially for central nervous system (CNS) targeted therapies.
• Medicinal Chemistry Research: Used as a core scaffold in drug discovery programs for structure-activity relationship (SAR) studies and lead optimization.
• Preclinical Development: Serves as a critical material for producing batches of candidate drugs for pharmacological and toxicological evaluation.
• Chemical Synthesis: Employed in asymmetric synthesis and chiral resolution processes to create enantiomerically enriched compounds.
• Reference Standard: Can be utilized as an analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name	(+-)-(R*,S*)-6-Fluoro-3,4-Dihydro-α-[[(Phenylmethyl)Amino]Methyl]-2H-1-Benzopyran-2-Methanol
CAS No.	99199-91-4
Molecular Formula	C19H22FNO2
Molecular Weight	315.38 g/mol
Synonyms	6-Fluoro-3,4-dihydro-α-[(phenylmethyl)amino]methyl]-2H-1-benzopyran-2-methanol; (±)-6-Fluoro-3,4-dihydro-α-[(phenylmethylamino)methyl]-2H-1-benzopyran-2-methanol; 2H-1-Benzopyran-2-methanol, 6-fluoro-3,4-dihydro-α-[[(phenylmethyl)amino]methyl]-, (±)-; Flunarizine Intermediate; Benzopyran Methanol Derivative; CAS 99199-91-4
EINECS	Contact for details

Quality Control

Our (+-)-(R*,S*)-6-Fluoro-3,4-Dihydro-α-[[(Phenylmethyl)Amino]Methyl]-2H-1-Benzopyran-2-Methanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, chiral composition, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.