Description

6-Fluoro-3,4-Dihydro-2-Oxiranyl-2H-1-Benzopyran is a high-value, multifunctional chiral building block and advanced pharmaceutical intermediate. This compound is critical for the synthesis of complex molecules, offering a unique fused benzopyran-oxirane scaffold with a fluorine substituent for fine-tuning biological activity and physicochemical properties. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel therapeutic agents, particularly in central nervous system (CNS) and cardiovascular drug candidates.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the fluorine atom and epoxide ring enhance bioactivity and environmental stability.
• Chemical Research: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Material Science Precursor: Potential use in synthesizing specialized polymers or liquid crystals due to its rigid, fused aromatic structure.
• Asymmetric Catalysis: The chiral epoxide moiety makes it a valuable starting material or ligand precursor in asymmetric synthesis.

Basic Information

Product Name	6-Fluoro-3,4-Dihydro-2-Oxiranyl-2H-1-Benzopyran
CAS No.	99199-90-3
Molecular Formula	C11H9FO2
Molecular Weight	192.19 g/mol
Synonyms	6-Fluoro-3,4-dihydro-2-oxiranyl-2H-1-benzopyran; 2-(6-Fluorochroman-2-yl)oxirane; 6-Fluoro-2-(oxiran-2-yl)chroman; 6-Fluorochroman-2-yloxirane; (6-Fluorochroman-2-yl)oxirane; 2-(6-Fluoro-3,4-dihydro-2H-chromen-2-yl)oxirane; 99199-90-3; Oxirane, 2-(6-fluoro-3,4-dihydro-2H-1-benzopyran-2-yl)-
EINECS	Contact for details

Quality Control

Our 6-Fluoro-3,4-Dihydro-2-Oxiranyl-2H-1-Benzopyran is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment, to ensure it meets the high standards required for pharmaceutical R&D and production. A comprehensive Certificate of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at 2-8°C for long-term stability. Allow the container to reach room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.