Description

2(S)-3-(2-Aminophenoxy)-2-((tert-Butoxycarbonyl)Amino)Propanoic Acid is a high-purity, protected amino acid derivative designed for advanced pharmaceutical synthesis and peptide research. This compound serves as a critical chiral building block, enabling the precise construction of complex molecules with defined stereochemistry. It is primarily utilized by research institutions and pharmaceutical manufacturers developing novel therapeutic peptides and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of complex peptide-based drugs and active pharmaceutical ingredients (APIs).
• Peptide Chemistry: Used in solid-phase and solution-phase peptide synthesis (SPPS) to introduce specific, orthogonally protected amino acid residues.
• Protease Inhibitor Development: Serves as a core structural component in the research and production of enzyme inhibitors.
• Chemical Biology Research: Employed in the study of protein-protein interactions and the development of bioactive peptide probes.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs producing bespoke compounds for client projects.
• Academic Research: Utilized in university and institutional labs for methodological development in organic and medicinal chemistry.

Basic Information

Product Name	2(S)-3-(2-Aminophenoxy)-2-((tert-Butoxycarbonyl)Amino)Propanoic Acid
CAS No.	99197-79-2
Molecular Formula	C14H20N2O5
Molecular Weight	296.32 g/mol
Synonyms	Boc-2-Amino-3-(2-aminophenoxy)propionic acid; (2S)-3-(2-Aminophenoxy)-2-[(tert-butoxycarbonyl)amino]propanoic acid; N-Boc-O-(2-aminophenyl)-L-serine; N-(tert-Butoxycarbonyl)-3-(2-aminophenoxy)-L-alanine; Boc-L-3-(2-Aminophenoxy)alanine; 99197-79-2; Boc-Amp(2-NH2)-OH
EINECS	Contact for details

Quality Control

Our production of 2(S)-3-(2-Aminophenoxy)-2-((tert-Butoxycarbonyl)Amino)Propanoic Acid adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity, suitable for sensitive pharmaceutical applications. All material is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, chiral integrity, and impurity profiles. We support compliance with cGMP, ICH Q7 guidelines, and relevant pharmacopeial standards where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed under an inert atmosphere after each use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.