Description

2-Amino-5-Pyrimidinesulfonamide is a high-purity, specialized heterocyclic sulfonamide building block of significant importance in advanced organic synthesis. Its core value lies in its bifunctional molecular structure, which serves as a critical precursor for the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. This compound is essential for research and production chemists in the pharmaceutical, agrochemical, and fine chemical industries seeking to incorporate a functionalized pyrimidine-sulfonamide scaffold into their target molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting enzymes where the sulfonamide moiety acts as a pharmacophore.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and plant growth regulators.
• Fine Chemical Production: Serves as a versatile precursor for creating complex molecules used in material science and specialty chemistry applications.
• Biochemical Research: Employed as a tool compound in medicinal chemistry for structure-activity relationship (SAR) studies and hit-to-lead optimization.
• Chemical Reference Standard: Supplied as a high-purity standard for analytical method development and quality control in manufacturing processes.

Basic Information

Product Name	2-Amino-5-Pyrimidinesulfonamide
CAS No.	99171-23-0
Molecular Formula	C4H6N4O2S
Molecular Weight	174.18 g/mol
Synonyms	5-Sulfamoylpyrimidin-2-amine; 2-Amino-5-sulfamoylpyrimidine; 2-Aminopyrimidine-5-sulfonamide; Pyrimidine-5-sulfonamide, 2-amino-; 5-Pyrimidinesulfonamide, 2-amino-; 99171-23-0; 2-Amino-5-sulfonylaminopyrimidine
EINECS	Contact for details

Quality Control

Our 2-Amino-5-Pyrimidinesulfonamide is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring the material meets the rigorous standards required for advanced synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and handling properties. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.