Description

2-Amino-3-[4-(Aminomethyl)Phenyl]Propanoic Acid is a specialized aromatic amino acid derivative featuring dual amino functionalities. This compound matters as a versatile and valuable pharmaceutical intermediate and building block for advanced organic synthesis. It is primarily needed by research institutions and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors for developing novel active compounds and peptide mimetics.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and metabolic disorder research.
• Peptidomimetic Synthesis: Used to construct non-natural amino acid residues in peptides to enhance stability, bioavailability, and biological activity.
• Ligand and Chelator Development: Serves as a precursor for creating specialized ligands and chelating agents used in catalysis and medicinal chemistry.
• Bioconjugation and Linker Chemistry: The reactive amino groups enable its use in creating linkers for antibody-drug conjugates (ADCs) and other bioconjugation applications.
• Chemical Biology Research: Employed as a probe or tool compound in studying enzyme mechanisms and protein-protein interactions.
• Fine Chemical Synthesis: A versatile intermediate for synthesizing complex organic molecules, dyes, and advanced materials.

Basic Information

Product Name	2-Amino-3-[4-(Aminomethyl)Phenyl]Propanoic Acid
CAS No.	99169-63-8
Molecular Formula	C10H14N2O2
Molecular Weight	194.23 g/mol
Synonyms	4-(Aminomethyl)-D-phenylalanine; 2-Amino-3-(4-(aminomethyl)phenyl)propanoic acid; D-4-(Aminomethyl)phenylalanine; (R)-2-Amino-3-(4-(aminomethyl)phenyl)propanoic acid; 4-(Aminomethyl)-D-Phe; 99169-63-8; 4-(Aminomethyl)-DL-phenylalanine (for racemic mixtures)
EINECS	Contact for details

Quality Control

Our 2-Amino-3-[4-(Aminomethyl)Phenyl]Propanoic Acid is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, detailing key parameters such as assay, chiral purity, and impurity profiles. Specifications can be tailored to meet cGMP and other stringent regulatory requirements for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent absorption of atmospheric moisture, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee (D-Isomer)
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.