Description

(n-Octanoylthio)Phosphatidylcholine is a specialized, synthetic phospholipid derivative where an octanoylthio moiety is covalently attached to the phosphatidylcholine backbone. This compound is valued for its unique amphiphilic properties and its role as a key intermediate or functional component in advanced biochemical and pharmaceutical research. It is primarily sought after by researchers and developers in the life sciences sector for applications in drug delivery systems, membrane studies, and as a building block for more complex lipid conjugates. The product is supplied under stringent quality control to ensure consistency for sensitive experimental and formulation work.

Application

• Liposome and Nanoparticle Formulation: Used as a functionalized lipid component to create targeted drug delivery vehicles with enhanced stability or specific release profiles.
• Membrane Biophysics Research: Serves as a tool for studying membrane fluidity, protein-lipid interactions, and the incorporation of thiol-reactive groups into lipid bilayers.
• Bioconjugation and Probe Synthesis: Acts as a critical intermediate for synthesizing fluorescently labeled or other tagged phospholipids for diagnostic and imaging applications.
• Model System for Oxidation Studies: Utilized in research investigating lipid peroxidation mechanisms and the protective effects of antioxidants due to its sensitive thioester linkage.
• Excipient Development: Explored for use in novel pharmaceutical formulations where a modified phospholipid can improve solubility or bioavailability of active ingredients.

Basic Information

Product Name	(n-Octanoylthio)Phosphatidylcholine
CAS No.	99165-87-4
Molecular Formula	C36H70NO8PS
Molecular Weight	708.0 g/mol (approx.)
Synonyms	1,2-Diacyl-sn-glycero-3-phosphocholine, Octanoylthio derivative; 1,2-Dioleoyl-sn-glycero-3-phospho-(1'-octanoylthio)choline; S-Octanoyl Phosphatidylcholine; Octanoylthio-PC; Thioester-modified Phosphatidylcholine; Phospholipid Octanoyl Thioester; 3-[(Octanoylthio)methyl]-1,2-diacylglycerophosphocholine
EINECS	Contact for details

Quality Control

Our (n-Octanoylthio)Phosphatidylcholine is produced and handled under a strict quality management system. Each batch undergoes comprehensive analytical testing, including chromatographic purity assessment and structural confirmation, to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) providing batch-specific data for identity, purity, and related substances is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to minimize oxidation and hydrolysis. The material is hygroscopic and moisture-sensitive; allow the sealed vial to equilibrate to room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white waxy solid or film
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Solubility	Soluble in chloroform, ethanol; sparingly soluble in aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.